So far, reports to CDC of breakthrough infections are exceedingly rare.

  • As of April 13, 2021, more than 75 million people in the United States had been fully vaccinated against COVID-19 since December 14, 2020.
  • During the same time, CDC received 5,814 reports of vaccine breakthrough infections (which is 0.008% of the 75 million people), 2,622 of which were among people ≥60 years of age.
  • 396 (7%) people with breakthrough infections were known to be hospitalized and 74 died.
  • Of the 396 hospitalized patients, 133 were reported as asymptomatic or hospitalized for a reason not related to COVID-19.
  • Of the 74 fatal cases, 9 were reported as asymptomatic or the patient died due to a cause not related to COVID-19.

It is important to note that reported vaccine breakthrough cases will represent an undercount (due to voluntary reporting and lack of testing in asymptomatic/mild illness). However, overall, this data is extremely positive.





New: April 21, 2021